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Implications of astrocytes in neurovascular coupling

You ZHOU MD, Chang-Kai SUN MD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 43-45 doi: 10.1007/s11684-010-0019-4

Abstract: The close spatial and temporal relationship between neural activity and cerebral blood flow (CBF) isThe increase in flow evoked by brain activity is mediated by the concerted action of multiple mediatorsthat originate from different cells and act at different levels of the cerebral vasculature.

Keywords： cerebral blood flow     neurovascular coupling     astrocyte    

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Ultrasound Blood Flow Non-invasive Detection and Characteristic Extraction of the Medical Signals

Wang Weiqi,Wang Yuanyuan,Yu Jianguo,Wu Xiaofeng,Liu Bin,Zhang Yu,Chen Sizhong,Yi Yanhua,Shao Qianming

Strategic Study of CAE 2001, Volume 3, Issue 2,   Pages 52-64

Abstract: In this paper, the quantitative blood flow velocity detection using the Doppler ultrasound techniquecirculation, the color-encoded spectrogram analyzer and the ultrasound quantitative detection system for the bloodflow velocity.

Keywords： ultrasound blood flow     medical signal     non-invasive detection     characteristic extraction    

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Non-invasive continuous blood pressure monitoring: a review of current applications

Elena Chung, Guo Chen, Brenton Alexander, Maxime Cannesson

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 91-101 doi: 10.1007/s11684-013-0239-5

Abstract:

Blood pressure monitoring has come a long way from the initial observations made by Reverend HalesThere are none that deny the importance of monitoring perioperative blood pressure; however, the limitedblood pressure measurements leaves room for improvement.Invasive monitoring is able to detect beat-to-beat blood pressure measurement, but the risks inherent, and especially the creation of those offering non-invasive but continuous blood pressure monitoring

Keywords： non-invasive blood pressure monitoring     continuous blood pressure monitoring     invasive blood pressure monitoring    

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Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profileand blood glucose level

TANG Zhongzhi, LI Junyao, YANG Jianhong

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 178-181 doi: 10.1007/s11684-008-0033-y

Abstract: To study the relationship of the polymorphism of endothelial nitric oxide synthase (eNOS) gene and bloodpressure, lipid profiles and blood glucose level.Taking into account eNOS Glu298Asp polymorphisms, the relationship of blood pressure with triglycerides(TG), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL) and bloodThe distribution of eNOS Glu298Asp polymorphism had no significant difference between different blood
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Overexpression of netrin-1 improves neurological outcomes in mice following transient middle cerebral

Haiyan LU, Yongting WANG, Falei YUAN, Jianrong LIU, Lili ZENG, Guo-Yuan YANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 86-93 doi: 10.1007/s11684-011-0118-x

Abstract: NT-1 was shown to be able to stimulate the proliferation and migration of human cerebral endothelialusing an adeno-associated virus (AAV) vector (AAV-NT-1) into mouse brain followed by transient middle cerebral

Keywords： adeno-associated virus     angiogenesis     gene transfer     ischemia     middle cerebral artery occlusion     netrin-1    

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Stroke prevention: an update

Marie-Germaine Bousser

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 22-34 doi: 10.1007/s11684-012-0178-6

Abstract: treatments addressing the specific subtypes of stroke, such as antiplatelet drugs for the prevention of cerebralRecent approaches include low cost intervention packages to reduce blood pressure and cheap “polypills” combining in a single tablet aspirin and several drugs to lower blood pressure and cholesterol

Keywords： stroke     prevention     vascular risk factors     cerebral infarction     cerebral hemorrhage     anti-thrombotic drugs    

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survival and neuronal differentiation of hypoxia-conditioned neuronal progenitor cells in rats with cerebral

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 472-485 doi: 10.1007/s11684-021-0832-y

Abstract: conditioning could increase the survival of transplanted neuronal progenitor cells (NPCs) in rats with cerebral

Keywords： neuronal progenitor cells     resveratrol     cerebral ischemia     neuronal differentiation     mitochondrial metabolism    

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White blood cell count and the incidence of hyperuricemia: insights from a community-based study

Jian Liu, Pingyan Shen, Xiaobo Ma, Xialian Yu, Liyan Ni, Xu Hao, Weiming Wang, Nan Chen

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 741-746 doi: 10.1007/s11684-017-0579-7

Abstract: The relationship between HUA and white blood cell (WBC) count remains unknown.

Keywords： white blood cell count     hyperuricemia     chronic kidney disease     inflammation    

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gelatin-heparin nanofibrous scaffolds formed by a bi-layer electrospinning technique as potential artificial blood

Heyun WANG, Yakai FENG, Marc BEHL, Andreas LENDLEIN, Haiyang ZHAO, Ruofang XIAO, Jian LU, Li ZHANG, Jintang GUO

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 3,   Pages 392-400 doi: 10.1007/s11705-011-1202-0

Abstract: In this paper, a scaffold, which mimics the morphology and mechanical properties of a native blood vesselbreaking strength (3.7±0.13 MPa) and an elongation at break (110±8%) that are appropriate for artificial bloodthe complex matrix structure of native arteries, and to have good biocompatibility as an artificial blood

Keywords： electrospinning     artificial blood vessels     scaffold     polyurethane     gelatin     nanofiber     hemocompatibility    

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Study of blood exposure-related mental health illness among clinical nurses

Xiaojia Xiong,Min Li,Yongliang Jiang,Xindeng Tong,Yanzhong Peng

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 147-151 doi: 10.1007/s11684-016-0481-8

Abstract: This study aims to investigate the mental health status of nurses exposed to blood through needlestickNo significant difference between nurses exposed to blood and nurses not exposed to blood was found inResults from the GHQ-28 Standardized Questionnaire showed that 75.9% (123/162) of nurses exposed to bloodwere suspected to suffer from mental disorders, whereas 40% (56/140) of nurses not exposed to bloodThe mean mental health scores of nurses exposed to blood and those not exposed were 8.73±7.32

Keywords： blood exposure     needlestick injuries     mental health     nurses    

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Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 336-340 doi: 10.1007/s11684-011-0163-5

Abstract: Endostatin, a 20 kDa C-terminal fragment of collagen XVIII, was first identified as a potent angiogenic inhibitor. The anti-angiogenic function of endostatin has been well documented during the past decade. Recently, several studies demonstrated that endostatin also inhibits tumor lymphangiogenesis and lymphatic metastasis. However, the exact mechanism that endostatin executes its anti-angiogenic and anti-lymphangiogenic functions remains elusive. In the current mini-review, we briefly summarize recent novel findings, including the functions of endostatin targeting not only angiogenesis but also lymphangiogenesis, and the underlying mechanism by which endostatin internalization regulates its biological functions.

Keywords： endostatin     angiogenesis     lymphangiogenesis     nystatin     internalization     tumor    

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Intracellular trehalose improves the survival of human red blood cells by freeze-drying

HE Hui, LIU Baolin, HUA Zezhao, LI Chuan, WU Zhengzheng

Frontiers in Energy 2007, Volume 1, Issue 1,   Pages 120-124 doi: 10.1007/s11708-007-0014-x

Abstract: Freeze-drying of human red blood cells has a potential important application for blood transfusion.aim of this study was to investigate the effects of intracellular trehalose on the survival of red bloodFresh red blood cells were incubated in trehalose solutions of various concentrations at 37vH for 7 h, and human serum albumin were used as extracellular protective agents for the freeze-drying of red bloodThe viability of freeze-dried red blood cells increased with the increment of intracellular trehalose
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Current Status of Blood Lipid Level and Prevention Strategy of Lipid Disorder in Chinese Population

Chen Haozhu,Jin Xuejuan

Strategic Study of CAE 2002, Volume 4, Issue 11,   Pages 1-6

Abstract: Results： (1)The levels of blood total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and

Keywords： blood lipids     epidemiology     prevention    

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Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 19-24 doi: 10.1007/s11684-008-0005-2

Abstract: is to investigate the effects of RNA interference (RNAi) targeting angiotensin 1a receptor (AT1a) on bloodadministration, pAT1a-shRNA1, pAT1a-shRNA2 and valsartan respectively resulted in decrease of the tail bloodHowever, the tail blood pressure increased further by about 25 mmHg in both of pCon and control groups

Keywords： therapy     Sprague     administration     cardiac hypertrophy     valsartan    

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Using hybrid models to predict blood pressure reactivity to unsupported back based on anthropometric

Gurmanik KAUR,Ajat Shatru ARORA,Vijender Kumar JAIN

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 6,   Pages 474-485 doi: 10.1631/FITEE.1400295

Abstract: Accurate blood pressure (BP) measurement is essential in epidemiological studies, screening programmes

Keywords： Blood pressure (BP)     Principal component analysis (PCA)     Forward stepwise regression     Artificial neural    

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Title Author Date Type Operation

Implications of astrocytes in neurovascular coupling

You ZHOU MD, Chang-Kai SUN MD,

Journal Article

Ultrasound Blood Flow Non-invasive Detection and Characteristic Extraction of the Medical Signals

Wang Weiqi,Wang Yuanyuan,Yu Jianguo,Wu Xiaofeng,Liu Bin,Zhang Yu,Chen Sizhong,Yi Yanhua,Shao Qianming

Journal Article

Non-invasive continuous blood pressure monitoring: a review of current applications

Elena Chung, Guo Chen, Brenton Alexander, Maxime Cannesson

Journal Article

Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profileand blood glucose level

TANG Zhongzhi, LI Junyao, YANG Jianhong

Journal Article

Overexpression of netrin-1 improves neurological outcomes in mice following transient middle cerebral

Haiyan LU, Yongting WANG, Falei YUAN, Jianrong LIU, Lili ZENG, Guo-Yuan YANG

Journal Article

Stroke prevention: an update

Marie-Germaine Bousser

Journal Article

survival and neuronal differentiation of hypoxia-conditioned neuronal progenitor cells in rats with cerebral

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Journal Article

White blood cell count and the incidence of hyperuricemia: insights from a community-based study

Jian Liu, Pingyan Shen, Xiaobo Ma, Xialian Yu, Liyan Ni, Xu Hao, Weiming Wang, Nan Chen

Journal Article

gelatin-heparin nanofibrous scaffolds formed by a bi-layer electrospinning technique as potential artificial blood

Heyun WANG, Yakai FENG, Marc BEHL, Andreas LENDLEIN, Haiyang ZHAO, Ruofang XIAO, Jian LU, Li ZHANG, Jintang GUO

Journal Article

Study of blood exposure-related mental health illness among clinical nurses

Xiaojia Xiong,Min Li,Yongliang Jiang,Xindeng Tong,Yanzhong Peng

Journal Article

Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Journal Article

Intracellular trehalose improves the survival of human red blood cells by freeze-drying

HE Hui, LIU Baolin, HUA Zezhao, LI Chuan, WU Zhengzheng

Journal Article

Current Status of Blood Lipid Level and Prevention Strategy of Lipid Disorder in Chinese Population

Chen Haozhu,Jin Xuejuan

Journal Article

Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Journal Article

Using hybrid models to predict blood pressure reactivity to unsupported back based on anthropometric

Gurmanik KAUR,Ajat Shatru ARORA,Vijender Kumar JAIN

Journal Article